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Index > Protein center > Synpo(Gene name) > Mouse
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  • Synpo (Gene name),
  • Synaptopodin (Protein name ),  SYNPO_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Synpo(Kiaa1029);
    Protein name:
    Synaptopodin;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with BAIAP1. Interacts with actin. Interacts (via PPxY motifs) with WWC1 (via WW domains).
    Function:
    Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell junction tight junction Perikaryon Cell projection dendritic spine Cell junction synapse postsynaptic cell membrane postsynaptic density Cell junction synapse Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
    Protein Attributes:
    Sequence length:
    929
    Sequence:
    50:
    MLGAHFPPPP | LGASEGRAAP | CTFQIPDGSY | RCLALEAEES | SSEDGLQGEV | 
    100:
    RLVDLEEEGT | SQSRANHGTP | PLSRAPAIIQ | PSSCHREARG | GFQRSDRPSH | 
    150:
    DWDVVQARKV | MTASGSSSPV | PRVAQKPALG | RSTSFTENDL | KEAKARSQQI | 
    200:
    AAQLTTPPSS | NSRGVQLFNR | RRQRVNEFTL | ESRGQRSPKL | NQEALQTGRP | 
    250:
    LSPIGHAPGP | SVKPTSPSKP | GSPKHPSPQS | PSRGVAGHIM | EGYSEEASLL | 
    300:
    RHLEKVASEE | EEVPLVVYLK | ENAALLTANG | LHLSQSRETQ | QSSPNPPDTE | 
    350:
    VPSPAADINQ | NPSSPNATLT | TLASSSHHSQ | PTADINQNPP | AAITPVPQNS | 
    400:
    SQAQCSPNGT | LDSKPGTLCA | DDGQSPVPAE | EVRSSILLID | KVSAPPSAAS | 
    450:
    TFSREATPLS | SSGPPAADLM | SSSLLIDMQP | STLVAPAEQE | VPGHVAVTTP | 
    500:
    TKVYSEVHLT | LAKPASVVNR | TARPFGIQSP | GTSQIEQSPM | MGRRQFGEKA | 
    550:
    WAPPASSMAD | RSPQPQRHIM | SRSPMVERRL | LGQRSPVLER | RPLGNFTPPP | 
    600:
    TYAETLSTAP | VASRVRSPPS | YSTLYPSSDP | KPSHLKGQVA | PANKTGILEE | 
    650:
    SMARRGSRKS | MFTFVEKPKV | TPNPDLLDLV | QTADEKRRQR | DHGEVGMEEE | 
    700:
    PFALGAEASN | FQQEPIARDR | ASPAAAEEAV | PEWASCLKSP | RIQAKPKPKP | 
    750:
    NQNLSEASGK | GAELYARRQS | RMEKYVIESS | GHAELARCPS | PTMSLPSSWK | 
    800:
    YTTNAPGGFR | VASLSPARTP | PASLYHGYLP | ENGVLRPEPT | KQQPYQMRPS | 
    850:
    LYALSPVKEP | AKASSRATSS | RTPSRTVSPR | AASPAKPSSL | DLVPNLPRAG | 
    900:
    LPPSPALPRP | SRSSPGLYTA | PVQDSLQPTA | VSPTYSSDIS | PVSPSRAWSP | 
    929:
    RAKQAPRPSF | STRNAGIEAQ | VWKPSFCFK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Synaptopodin
    Cat.:
    E1122h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Synaptopodin
    Cat.:
    E1122r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Synaptopodin
    Cat.:
    E1122m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Synaptopodin
    Cat.:
    U1122r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Synaptopodin
    Cat.:
    U1122h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Synaptopodin
    Cat.:
    U1122m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Synaptopodin
    Cat.:
    P1122Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Synaptopodin
    Cat.:
    P1122Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Synaptopodin
    Cat.:
    P1122Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Synaptopodin
    Monoclonal Antibody for Mouse Synaptopodin
    Monoclonal Antibody for Mouse Synaptopodin
    Protein for Mouse Synaptopodin
    Protein for Mouse Synaptopodin
    Protein for Mouse Synaptopodin

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    Precision
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    2. 2.
      The MGC Project Team
      Submitted (2003-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-203 (ISOFORM 1)
      tissue: Brain.
    3. 3.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 392-404; 567-586 AND 751-760;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    4. 4.
      "Full-length sequencing of some human and murine muscular transcripts (Telethon Italy project B41)."
      Ievolella C. , Zara I. , Millino C. , Faulkner G. , Lanfranchi G.
      Submitted (2000-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 863-929 (ISOFORMS 1/3)
      tissue: Skeletal muscle.
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 921-929 (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Diencephalon.
    6. 6.
      "Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes."
      Mundel P. , Heid H.W. , Mundel T.M. , Krueger M. , Reiser J. , Kriz W.
      J. Cell Biol.139:193-204(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ACTIN;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    7. 7.
      "Laminar distribution of synaptopodin in normal and reeler mouse brain depends on the position of spine-bearing neurons."
      Deller T. , Haas C.A. , Deissenrieder K. , Del Turco D. , Coulin C. , Gebhardt C. , Drakew A. , Schwarz K. , Mundel P. , Frotscher M.
      J. Comp. Neurol.453:33-44(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      "Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity."
      Deller T. , Korte M. , Chabanis S. , Drakew A. , Schwegler H. , Stefani G.G. , Zuniga A. , Schwarz K. , Bonhoeffer T. , Zeller R. , Frotscher M. , Mundel P.
      Proc. Natl. Acad. Sci. U.S.A.100:10494-10499(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    9. 9.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-258 AND SER-672;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    10. 10.
      "O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry."
      Vosseller K. , Trinidad J.C. , Chalkley R.J. , Specht C.G. , Thalhammer A. , Lynn A.J. , Snedecor J.O. , Guan S. , Medzihradszky K.F. , Maltby D.A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:923-934(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS]
      tissue: Brain.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-833;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    12. 12.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-672 AND SER-833;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-789 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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